IverMed-12, 36 Tablets

IverMed-12:

Dr. Satoshi Omura, the scientist that discovered Ivermectin, won the 2015 Nobel Prize in Medicine.  It is fair to classify this as a life saving miracle compound!

Ivermectin since its introduction has continually proven to be astonishingly safe for human use.

Indeed, it is ideal in many ways, being very safe, highly effective, broad-spectrum, and well tolerated. It is such a safe drug, and with such minimal side effects, that it can be easily administered by non-medical staff and even illiterate individuals in remote rural communities.

Ivermectin is a broad-spectrum and potent anti-viral compound. Millions of lives could have been saved during the covid-19 era using Ivermectin as a preventative or as a curative. 

After misleading the public, and maligning the character and reputation of ethical physicians across America, the US FDA was ordered to remove all social media posts and misleading consumer directives regarding Ivermectin and COVID.  According to Dr Paul E. Marik, MD, CSO of the FLCCC Alliance, “The FDA interfered in the practice of medicine with their irresponsible language and posts about Ivermectin. We will never know how many lives were affected because patients were denied access to a lifesaving treatment.” 

There is a continuously accumulating body of evidence that Ivermectin has substantial value in the treatment of a variety of cancers. A steadily increasing number of reports indicate that Ivermectin has varying uses as an anti-cancer and anti-tumour agent. (2)

Furthermore, according to Dr. Paul Makis MD, Ivermectin has been shown to kill cancer cells involved in the top 5 COVID-19 mRNA Vaccine Induced Turbo Cancers including: (3)

1. lymphomas
2. brain cancers
3. breast cancers
4. colon cancers
5. lung cancers 

Lesser signals have also been seen in leukemias, hepatobiliary cancers, testicular cancers, sarcomas and melanomas.

Reported invitro laboratory experiments, Ivermectin has been shown to be able to kill cancer cells of many types, such as

1. Breast Cancer
2. Ovarian Cancer
3. Prostate Cancer
4. Colorectal Cancer
5. Brain Cancer
6. Renal Cancer
7. Leukemia
8. AML
9. Hepatocellular carcinoma
10. Lung Cancer

Academic research has indicated that Ivermectin can address many more mechanism that can lead to tumor suppression. Whether all or some of those mechanisms have at the base its ionophore activity remains to be seen.

Nevertheless, the list of anti cancer mechanisms related to Ivermectin is outstanding:

1. Can trigger “Immunogenic Cancer Cell Death”. This is a form of cancer cell death that “wakes up” the immune system and therefore initiates an immune response. As a result, it has been proposed that Ivermectin coudl be a great combination with forms of immuno therapy such as checkpoint inhibitors.
2. Downregulates glutathione S-transferases (GSTs) and vascular endothelial growth factor (VEGF)
3. Potentiated activity of anti–androgen receptor and anti-EGFR drugs
4. Inhibited cancer stem‑like cells (CSC)
5. Inhibits angiogenesis
6. Inhibition of metastasis
7. WNT pathway inhibitor
8. Increased reactive oxygen species generation that was functionally important for ivermectin-induced cell death
9. Microtubule inhibitor
10. Multi Drug Resistance Pumps inhibitor
11. At a higher dose, Ivermectin can inactivate the protein kinase PAK1 and blocks the PAK1 dependent growth – PAK1 is critical for cytoskeleton reorganization and nuclear signalling. PAK-1 kinase is required for the growth of more than 70% of human cancers. This activity is similar to Caffeic Acid from Propolis.

This amazing list of activity explains why Ivermectin has such as large anti cancer potential.

Furthermore, Ivermectin may be used as a preventative measure using a single dose per week to avoid parasitic and viral infections. Prevention is a key tool in maintaining your health and wellness.

Elevated Healing’s IverMed-12 is compounded purposely to not contain any preservatives such as benzyl benzoate, benzoic acid, benzalkonium chloride, chlorhexidine, or butylated hydroxyanisole.

These substances will cause negative reactions over time with patients using higher doses of ivermectin. There are also no dyes used to colour the tablets including the highly poisonous tartazine (Red No 5). 

These toxic substances are all found in most Indian sourced products.

Also please note:

All liquid ivermectin preparations including liquid, paste and creams are not fit for human consumption. Ivermectin is completely insoluble in water and therefore solvents must be added to create an aqueous solution. The overwhelmingly most common product used is Polysortbate 80 which is highly inflammatory and has been proven to cause inflammatory bowel disorders and is one of the leading causes of leaky gut syndrome. Additionally, the ivermectin used in veterinarian preparations will be at the low end of purity in the high 80% range. Human grade GMP product must exceed 96% – the raw material used in IverMed-12 is 98.6% pure.

References:

1. Crump A, Ōmura S. Ivermectin, ‘wonder drug’ from Japan: the human use perspective. Proc Jpn Acad Ser B Phys Biol Sci. 2011;87(2):13-28. doi: 10.2183/pjab.87.13. PMID: 21321478; PMCID: PMC3043740. 
2. Crump, A. Ivermectin: enigmatic multifaceted ‘wonder’ drug continues to surprise and exceed expectations. J Antibiot 70, 495–505 (2017). 
3. https://www.globalresearch.ca/ivermectin-15-anti-cancer-mechanisms-action-treat-covid-19-mrna-vaccine-induced-turbo-cancers/5834622
4. Kwon YJ, Petrie K, Leibovitch BA, Zeng L, Mezei M, Howell L, Gil V, Christova R, Bansal N, Yang S, Sharma R, Ariztia EV, Frankum J, Brough R, Sbirkov Y, Ashworth A, Lord CJ, Zelent A, Farias E, Zhou MM, Waxman S. Selective Inhibition of SIN3 Corepressor with Avermectins as a Novel Therapeutic Strategy in Triple-Negative Breast Cancer. Mol Cancer Ther. 2015 Aug;14(8):1824-36. doi: 10.1158/1535-7163.MCT-14-0980-T. Epub 2015 Jun 15. PMID: 26078298; PMCID: PMC4529816.
5. Juarez M, Schcolnik-Cabrera A, Dominguez-Gomez G, Chavez-Blanco A, Diaz-Chavez J, Duenas-Gonzalez A. Antitumor effects of ivermectin at clinically feasible concentrations support its clinical development as a repositioned cancer drug. Cancer Chemother Pharmacol. 2020 Jun;85(6):1153-1163. doi: 10.1007/s00280-020-04041-z. Epub 2020 May 30. PMID: 32474842.
6. Dominguez-Gomez G, Chavez-Blanco A, Medina-Franco JL, Saldivar-Gonzalez F, Flores-Torrontegui Y, Juarez M, Díaz-Chávez J, Gonzalez-Fierro A, Dueñas-González A. Ivermectin as an inhibitor of cancer stem‑like cells. Mol Med Rep. 2018 Feb;17(2):3397-3403. doi: 10.3892/mmr.2017.8231. Epub 2017 Dec 8. PMID: 29257278.
7. Zhou Shican , Wu Hang , Ning Wenjuan , Wu Xiao , Xu Xiaoxiao , Ma Yuanqiao , Li Xingwang , Hu Junhong , Wang Chenyu , Wang Junpeng, Ivermectin has New Application in Inhibiting Colorectal Cancer Cell Growth, Frontiers in Pharmacology, Volume 12 – 2021, https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2021.717529, DOI=10.3389/fphar.2021.71752, ISSN=1663-9812
8. Lee H, Kang S, Kim W. Drug Repositioning for Cancer Therapy Based on Large-Scale Drug-Induced Transcriptional Signatures. PLoS One. 2016 Mar 8;11(3):e0150460. doi: 10.1371/journal.pone.0150460. PMID: 26954019; PMCID: PMC4783079.
9. Lu H, Zhou L, Zuo H, Le W, Hu J, Zhang T, Li M, Yuan Y. Ivermectin synergizes sorafenib in hepatocellular carcinoma via targeting multiple oncogenic pathways. Pharmacol Res Perspect. 2022 Jun;10(3):e00954. doi: 10.1002/prp2.954. PMID: 35568994; PMCID: PMC9107598.
10. Zhu M, Li Y, Zhou Z. Antibiotic ivermectin preferentially targets renal cancer through inducing mitochondrial dysfunction and oxidative damage. Biochem Biophys Res Commun. 2017 Oct 21;492(3):373-378. doi: 10.1016/j.bbrc.2017.08.097. Epub 2017 Aug 25. PMID: 28847725.
11. Sharmeen S, Skrtic M, Sukhai MA, Hurren R, Gronda M, Wang X, Fonseca SB, Sun H, Wood TE, Ward R, Minden MD, Batey RA, Datti A, Wrana J, Kelley SO, Schimmer AD. The antiparasitic agent ivermectin induces chloride-dependent membrane hyperpolarization and cell death in leukemia cells. Blood. 2010 Nov 4;116(18):3593-603. doi: 10.1182/blood-2010-01-262675. Epub 2010 Jul 19. PMID: 20644115.
12. Draganov D, Han Z, Rana A, Bennett N, Irvine DJ, Lee PP. Ivermectin converts cold tumors hot and synergizes with immune checkpoint blockade for treatment of breast cancer. NPJ Breast Cancer. 2021 Mar 2;7(1):22. doi: 10.1038/s41523-021-00229-5. PMID: 33654071; PMCID: PMC7925581.
13. Siddiqui AJ, Khan MF, Hamadou WS, Goyal M, Jahan S, Jamal A, Ashraf SA, Sharma P, Sachidanandan M, Badraoui R, Chaubey KK, Snoussi M, Adnan M. Molecular Docking and Dynamics Simulation Revealed Ivermectin as Potential Drug against Schistosoma-Associated Bladder Cancer Targeting Protein Signaling: Computational Drug Repositioning Approach. Medicina (Kaunas). 2021 Oct 3;57(10):1058. doi: 10.3390/medicina57101058. PMID: 34684095; PMCID: PMC8539496.
14. Nappi L, Aguda AH, Nakouzi NA, Lelj-Garolla B, Beraldi E, Lallous N, Thi M, Moore S, Fazli L, Battsogt D, Stief S, Ban F, Nguyen NT, Saxena N, Dueva E, Zhang F, Yamazaki T, Zoubeidi A, Cherkasov A, Brayer GD, Gleave M. Ivermectin inhibits HSP27 and potentiates efficacy of oncogene targeting in tumor models. J Clin Invest. 2020 Feb 3;130(2):699-714. doi: 10.1172/JCI130819. PMID: 31845908; PMCID: PMC6994194.
15. Dominguez-Gomez G, Chavez-Blanco A, Medina-Franco JL, Saldivar-Gonzalez F, Flores-Torrontegui Y, Juarez M, Díaz-Chávez J, Gonzalez-Fierro A, Dueñas-González A. Ivermectin as an inhibitor of cancer stem‑like cells. Mol Med Rep. 2018 Feb;17(2):3397-3403. doi: 10.3892/mmr.2017.8231. Epub 2017 Dec 8. PMID: 29257278.
16. Liu Y, Fang S, Sun Q, Liu B. Anthelmintic drug ivermectin inhibits angiogenesis, growth and survival of glioblastoma through inducing mitochondrial dysfunction and oxidative stress. Biochem Biophys Res Commun. 2016 Nov 18;480(3):415-421. doi: 10.1016/j.bbrc.2016.10.064. Epub 2016 Oct 19. PMID: 27771251.
17. Kwon YJ, Petrie K, Leibovitch BA, Zeng L, Mezei M, Howell L, Gil V, Christova R, Bansal N, Yang S, Sharma R, Ariztia EV, Frankum J, Brough R, Sbirkov Y, Ashworth A, Lord CJ, Zelent A, Farias E, Zhou MM, Waxman S. Selective Inhibition of SIN3 Corepressor with Avermectins as a Novel Therapeutic Strategy in Triple-Negative Breast Cancer. Mol Cancer Ther. 2015 Aug;14(8):1824-36. doi: 10.1158/1535-7163.MCT-14-0980-T. Epub 2015 Jun 15. PMID: 26078298; PMCID: PMC4529816.
18. Melotti A, Mas C, Kuciak M, Lorente-Trigos A, Borges I, Ruiz i Altaba A. The river blindness drug Ivermectin and related macrocyclic lactones inhibit WNT-TCF pathway responses in human cancer. EMBO Mol Med. 2014 Oct;6(10):1263-78. doi: 10.15252/emmm.201404084. PMID: 25143352; PMCID: PMC4287931.
19. Sharmeen S, Skrtic M, Sukhai MA, Hurren R, Gronda M, Wang X, Fonseca SB, Sun H, Wood TE, Ward R, Minden MD, Batey RA, Datti A, Wrana J, Kelley SO, Schimmer AD. The antiparasitic agent ivermectin induces chloride-dependent membrane hyperpolarization and cell death in leukemia cells. Blood. 2010 Nov 4;116(18):3593-603. doi: 10.1182/blood-2010-01-262675. Epub 2010 Jul 19. PMID: 20644115.
20. Liu J, Zhang K, Cheng L, Zhu H, Xu T. Progress in Understanding the Molecular Mechanisms Underlying the Antitumour Effects of Ivermectin. Drug Des Devel Ther. 2020 Jan 21;14:285-296. doi: 10.2147/DDDT.S237393. PMID: 32021111; PMCID: PMC6982461.